Exploring the Role of the BCL-2 Family in Haematopoiesis and Haematopoietic Malignancy
Grant number: 1090500 | Funding period: 2015 - 2019
Completed
Abstract
Chronic Lymphocytic Leukaemia and Non-Hodgkin Lymphoma comprise the majority of blood cancers and are both disease in which the cell death pathway plays a vital role in both the development of the cancer cell and the resistance to chemotherapy. This project aims to examine the mechanisms of cancer in these tumours focussing on lymphoid cancers, and examine the role of new treatments targeting this pathway.